Brown:Journal club:Synthetic biology journal club


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18 July

Jason to present. More info soon.

11 July

Brendan to present on Article titled Ultrasensitivity and Nosie Propagation in a Synthetic Transcriptional Cascade.

PDF of Article

5 July

Peter presents an article about transcriptional regulators used to form an oscillator. The article is here


20 June

Hayato presents an article on producing the luciferace-magnetic particle complex.

6pm Walter Hall

16 May

This is the last journal club until the summer. This week will be a meeting to discuss the lab and the first few weeks of the summer. In Walter Hall, 80 Waterman, 6-7pm

9 May

Journal Club is in Walter Hall, 80 Waterman

Hiyato to present: Nanoparticle labels in immunosensing using optical detection methods

Matthias Seydack

2 May

Sri Kosuri from MIT to come and talk about his paper from the previous week.

25 April

John to present, + overview of Biobricks

Refactoring bacteriophage T7 Leon Y Chan1,a, Sriram Kosuri2,a and Drew Endy2

18th April

Kara and Jesse

Programmable ligand-controlled riboregulators of eukaryotic gene expression.

Bayer TS, Smolke CD.

11th April

Annie and Angela will present the article: "Design of artificial cell–cell communication using gene and metabolic networks".

The paper can be found at:

Thomas Bulter, Sun-Gu Lee, Wilson WaiChun Wong, Eileen Fung, Michael R. Conner, and James C. Liao. 2004. Design of artificial cell-cell communication using gene and metabolic networks. PNAS. 101(8): 2299-2304. (Quorum sensor using acetate signal).

4th April

Brendan and Peter will be presenting the article entitled "Engineering a mevalonate pathway in Escherichia coli for production of terpenoids".

Vincent J J Martin, Douglas J Pitera1, Sydnor T Withers1, Jack D Newman & Jay D Keasling. "Engineering a mevalonate pathway in Escherichia coli for production of terpenoids." Nature Biotechnology 21, 796 - 802 (2003).

It can be found online at

21st March

Megan and Victoria will present the article handed out in last meeting. Article is entitled: "Construction of a genetic toggle switch in Escherichia coli"

Timothy S. Gardner, Charles R. Cantor, and James J. Collins. 2000. Construction of a genetic toggle switch in Escherichia coli. Nature. Vol. 403. 339 - 342. (Bistable gene regulatory network, toggled by transient chemical or thermal induction, to serve as cellular memory) Download the paper here

14th March

John to give overview of last year's competition and to hand out readings Download paper here

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