Brown:March142006

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Contents

Meeting Minutes for March 14, 2006

Assignment of roles

Community Maker - Nick, Megan

Notetaker/Organizer (Secretary) - Angela

Journal Club Coordinator - Elena

Fundraising/PR

  • Julie: Fundraising, Sheldon
  • Brendan: PR
  • Elaine: helping both

Faculty Liaison - Victoria

Wiki Development - Peter

Research - Annie, Sheldon

"Benevolent Dictator" =) - John

Commercialization Potential (patents, etc)

Industry Laison

We have lab space in JWW!!!

Meeting Minutes for March 21, 2006

Present: John, Kara, Angela, Annie, Jessie, Peter, Brendan, Katherine, Victoria, Meghan

Journal Club Presentation

Construction of a Genetic Toggle Switch in E. Coli

by Victoria and Meghan

  • purpose: to integrate theory and experiment by constructing and testing a synthetic, bistable gene circuit (Toggle switch) based on the predictions of a simple mathematical model
  • integrate (mathetic) theory and (biology) experiment
  • mathematical models supposed to predict how much transcribed, testing expected outcomes
  • took a switch that self-regulates and has inducer (heat, chemical) that starts
  • prediction was wrong due to gene variability
  • simplest, as few reagents as possible better
  • specialized promoters
  • ribozyme binding sites, harnessed in plasmid; ensure that they are turned into proteins individually
  • genetic engineering (memory device) insert into something that you would want to be turned on for a long time
  • registry of biological parts at MIT; biological switch, wire linked together (electronic diagramà biological diagram

ACTIONS

  • Victoria will go to SAO to get info about table for ADOCH
  • possibly also a web page/link to Brown iGEM
  • have a site for prospective students to see who we are, as well as our contact info
  • also, for everyone: think of ways to gain more attention
  • Everyone: create a section on the wiki for the category you are overseeing
  • Create a community portal:
    • serve as a site that can be linked possibly from admissions page
    • emphasizing that we are cross-disciplinary undergraduates performing research at Brown University, even several freshmen involved
    • have our slightly more colorful biolographical infos attached
  • Possible ideas for our project?
  • Victoria/Megan doing the Journal Club presentation next week.
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