ETH 2006 Ideas

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[http://csb.inf.ethz.ch/igem-2006 life demo]
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Last years brainstorming: [[Previous_Ideas]]
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=== Cellular automata / Quorum controlled behaviour ===
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* Game of Life or other semitotalistic automata
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** [http://en.wikipedia.org/wiki/Conway%27s_Game_of_Life wikipedia]
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** [http://csb.inf.ethz.ch/igem-2006 life demo]
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** [http://www.ics.uci.edu/~eppstein/ca/lifelike.html others]
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* propagate a pulse in culture
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* Predator-prey-veggies (or just predator-prey)
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State representation:
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* switches and reporters
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* cell life (self destruct and regenerate)
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Stepping could be done by
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* an exogenious signal, so each step is a process converging to a steady state (avoid problem of developing a dynamic system)
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* generations
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* oscillating system in cells
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(Normally cellular automata are stepped synchronously, but it's often not really necessary)
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The matrix would not be as regular as in the mathematical models of corse ...
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=== Logic ===
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* A kind of a simple ALU: at least two simple logic functions and a multiplexer
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* An implementation of a full-adder: 1-bit adder with carry
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Can't find any logic gates except inverters in the registry, looks interesting.
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: → because of that, even simplier gates (AND, OR, XOR, ...) are required
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=== Sensing ===
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* acoustic
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* pressure
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* electric
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* magnetic (exists in nature, cf. [http://magnum.mpi-bremen.de/magneto/pub/Schueler1999.pdf])
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* light (BB exists[http://partsregistry.org/Featured_Parts:Light_Sensor])
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* temperature (first BBs by 2005 Toronto team [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Toronto])
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* chemicals
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* number of neighbor cells (related to «Game of Life» idea): it seems that another team tried similar in 2004 [http://2006.igem.org/wiki/index.php/IAP2004:Polkadorks]
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=== Oscillation related ===
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* frequency discrimination
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* synchronize oscillations among cells (or have emergent synchronous oscillations in the culture)
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=== Agents (sense & act) ===
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* fire squad: get bacteria to find a reaction on the plate and extinguish it
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* bacteria sensing high atmoshpere and switching to produce ozon (to refill ozon holes)
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=== Limitations to lift ===
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* E. coli can't move (Seems Penn state had moving E. Coli last year: [[Penn_StateProjectDes]])
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* need to control growth to stabilize cell culture structures if they are desired

Revision as of 13:58, 14 July 2006

Last years brainstorming: Previous_Ideas

Contents

Cellular automata / Quorum controlled behaviour

  • Game of Life or other semitotalistic automata
  • propagate a pulse in culture
  • Predator-prey-veggies (or just predator-prey)

State representation:

  • switches and reporters
  • cell life (self destruct and regenerate)

Stepping could be done by

  • an exogenious signal, so each step is a process converging to a steady state (avoid problem of developing a dynamic system)
  • generations
  • oscillating system in cells

(Normally cellular automata are stepped synchronously, but it's often not really necessary)

The matrix would not be as regular as in the mathematical models of corse ...

Logic

  • A kind of a simple ALU: at least two simple logic functions and a multiplexer
  • An implementation of a full-adder: 1-bit adder with carry

Can't find any logic gates except inverters in the registry, looks interesting.

→ because of that, even simplier gates (AND, OR, XOR, ...) are required

Sensing

  • acoustic
  • pressure
  • electric
  • magnetic (exists in nature, cf. [1])
  • light (BB exists[2])
  • temperature (first BBs by 2005 Toronto team [3])
  • chemicals
  • number of neighbor cells (related to «Game of Life» idea): it seems that another team tried similar in 2004 [4]

Oscillation related

  • frequency discrimination
  • synchronize oscillations among cells (or have emergent synchronous oscillations in the culture)

Agents (sense & act)

  • fire squad: get bacteria to find a reaction on the plate and extinguish it
  • bacteria sensing high atmoshpere and switching to produce ozon (to refill ozon holes)

Limitations to lift

  • E. coli can't move (Seems Penn state had moving E. Coli last year: Penn_StateProjectDes)
  • need to control growth to stabilize cell culture structures if they are desired
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