ETH 2006 Ideas
From 2006.igem.org
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=== Sensing === | === Sensing === | ||
| + | ==== What? ==== | ||
* acoustic | * acoustic | ||
* pressure | * pressure | ||
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* light (BB exists[http://partsregistry.org/Featured_Parts:Light_Sensor]) | * light (BB exists[http://partsregistry.org/Featured_Parts:Light_Sensor]) | ||
* temperature (first BBs by 2005 Toronto team [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Toronto]) | * temperature (first BBs by 2005 Toronto team [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Toronto]) | ||
| - | * chemicals | + | * chemicals, metals |
* number of neighbor cells (related to «Game of Life» idea): it seems that another team tried similar in 2004 [http://2006.igem.org/wiki/index.php/IAP2004:Polkadorks] | * number of neighbor cells (related to «Game of Life» idea): it seems that another team tried similar in 2004 [http://2006.igem.org/wiki/index.php/IAP2004:Polkadorks] | ||
| + | |||
| + | ==== Agents (sense & act) ==== | ||
| + | |||
| + | * fire squad: get bacteria to find a reaction on the plate and extinguish it | ||
| + | * bacteria sensing high atmoshpere and switching to produce ozon (to refill ozon holes) | ||
| + | * extract sun milk when needed (depending on sun intensity & skin properties :-) ) | ||
| + | |||
| + | ==== Multi-level sensing ==== | ||
| + | |||
| + | * a system which has more than on/off levels, e.g. | ||
| + | ** does nothing if ligand is not present | ||
| + | ** turns green on low concentrations | ||
| + | ** starts ''stinking'' (e.g. by producing ammonium) on high concentrations | ||
=== Oscillation related === | === Oscillation related === | ||
Revision as of 17:09, 17 July 2006
Last years brainstorming: Previous_Ideas
Contents |
Cellular automata / Quorum controlled behaviour
- Game of Life or other semitotalistic automata
- propagate a pulse in culture
- Predator-prey-veggies (or just predator-prey)
State representation:
- switches and reporters
- cell life (self destruct and regenerate)
Stepping could be done by
- an exogenious signal, so each step is a process converging to a steady state (avoid problem of developing a dynamic system)
- generations
- oscillating system in cells
(Normally cellular automata are stepped synchronously, but it's often not really necessary)
The matrix would not be as regular as in the mathematical models of corse ...
Logic
- A kind of a simple ALU: at least two simple logic functions and a multiplexer
- An implementation of a full-adder: 1-bit adder with carry
- An irreversible switch (lambda phage like)
Notes
Can't find any logic gates except inverters in the registry, looks interesting.
- → because of that, even simplier gates (AND, OR, XOR, ...) are required
Sensing
What?
- acoustic
- pressure
- electric
- magnetic (exists in nature, cf. [1])
- light (BB exists[2])
- temperature (first BBs by 2005 Toronto team [3])
- chemicals, metals
- number of neighbor cells (related to «Game of Life» idea): it seems that another team tried similar in 2004 [4]
Agents (sense & act)
- fire squad: get bacteria to find a reaction on the plate and extinguish it
- bacteria sensing high atmoshpere and switching to produce ozon (to refill ozon holes)
- extract sun milk when needed (depending on sun intensity & skin properties :-) )
Multi-level sensing
- a system which has more than on/off levels, e.g.
- does nothing if ligand is not present
- turns green on low concentrations
- starts stinking (e.g. by producing ammonium) on high concentrations
- frequency discrimination
- synchronize oscillations among cells (or have emergent synchronous oscillations in the culture)
- frequency divider / multiplier
Agents (sense & act)
- fire squad: get bacteria to find a reaction on the plate and extinguish it
- bacteria sensing high atmoshpere and switching to produce ozon (to refill ozon holes)
- extract sun milk when needed (depending on sun intensity & skin properties :-) )
Limitations to lift
- E. coli can't move (Seems Penn state had moving E. Coli last year: Penn_StateProjectDes)
- need to control growth to stabilize cell culture structures if they are desired
Misc
- optical lenses: program different (light) refraction angles
- fractals: let the bacteria culture grow such that fractal patterns appear
