User:Monak
From 2006.igem.org
- Design Rules -
To get it clear for myself (as a person without any prior knowledge about the steric hybridization properties of DNA), I tried to set up some simple, engineering point-of-view rules for designing a plain sheet of DNA.
- 2D DNA sheet of more or less arbitrary shape (click here)
- Individual project -
Smart materials from DNA
For example by self-assembly of folded and connected DNA sheets, which will change their physical properties with environmental changes, e.g. pH. (click here)
Wafer level nano-resolution pattern transfer
To start from the very basics, produce a plane sheet, and a sheet that folds once. For double-checking possibilitiy, we included a step-height variation that should appear in the AFM image, and a correlation fluorescence dye.
The plain sheet
This shall be the kick-off starting point to get into the business of DNA origami and employing it for nm-scale pattern transfer.
1. The step should be visible in the AFM image
2. We should be able to get a high signal for correlation fluorescence microscopy.
Pattern transfer?? Lot's of different possibilities that we want to give a try. But first, we have to be able to produce the very basics. The story will be continued..!
- Personal information -
e-mail: mona.klein@imtek.uni-freiburg.de
- Education -
Just graduated from the department of Microsystems Engineering.
Diploma-thesis (6-month compressed master's thesis) dealt with the fabrication of a solenoidal coil for MRI of cells.
[http://2006.igem.org/wiki/index.php/Freiburg_University_2006 Home]
