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<BIG><B>iGEM 2005</B></BIG>
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The summer 2005 intercollegiate Genetically Engineered Machine competition.
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==Participating Schools==
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''Click to see each team's parts''
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Berkeley Berkeley]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Caltech Caltech]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Cambridge Cambridge]
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===Davidson College Synth-Aces===
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====[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Davidson Davdison Parts in Registry]====
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[http://www.bio.davidson.edu/courses/synthetic/students.html '''Summer 2005 Research Students''']
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*'''Links to Courses'''
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**[http://www.bio.davidson.edu/courses/synthetic/synthetic.html Synthetic Lab Course Fall 2005]
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**[http://www.bio.davidson.edu/genomics Genomics Lecture Course (with Systems Biology and Synthetic Biology Sections)]
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**[http://www.bio.davidson.edu/programs/Genomics/concentration.html Genomics Concentration (interdiciplinary minor)]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_ETHZ ETH_Zurich]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Harvard Harvard]
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If you would like help setting up a '''[http://karma.med.harvard.edu/wiki/iGEM_2005 WIKI]''', please, contact [http://karma.med.harvard.edu/wiki/User_talk:Alexanderwait me]!
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_MIT MIT]
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**[http://model.mit.edu/igem/ MIT team's WIKI]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Oklamhoma Oklahoma]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Penn_State Penn State]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Princeton Princeton]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Toronto Toronto]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_UCSF UCSF]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_UTAustin UT Austin]
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*[http://rosalind.csail.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Registry Registry]
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==Events==
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*[http://rosalind.csail.mit.edu/r/parts/htdocs/iGEM2005/ttt.cgi Teacher's Workshop] - May 15-15, 2005
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**[[Parts, Devices, Systems & Engineering Theory]]
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**[[Risks and Rewards]]
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**[[Notes on Tom Knight's talk]]
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**[http://web.mit.edu/endy/www/scraps/talks/iGEM/Silver.yeast.ppt Pam Silver's yeast powerpoint]
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*Jamboree, November 5-6, 2005 (to change the name of the Jamboree, please send Drew Endy a check for $30,000,000)
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==Papers for Students to Read==
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===General Review Papers===
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*A. Malcolm Campbell. 2005. Meeting Report: Synthetic Biology Jamboree for Undergraduates. Cell Biology Education. 4: 19 - 23. (Meeting Report for 2004 Jamboree) [http://www.cellbioed.org/pdf/04-11-0047.pdf URL]
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*Dan Ferber. 2004. Microbes Made to Order. Science. Vol. 303: 158 - 161. (Good general overview), [http://www.sciencemag.org/cgi/content/full/303/5655/158 URL]
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*Jeff Hasty, David McMillen, and J. J. Collins. 2002. Engineered Gene Circuits. Nature. Vol. 420: 224 - 230. (Scholarly Review Paper), [http://www.nature.com/nature/journal/v420/n6912/abs/nature01257_fs.html URL]
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*Philip Ball. 2004. Starting from Scratch. Nature. Vol. 431: 624 - 626. (OK general overview), [http://www.nature.com/news/2004/041004/pf/431624a_pf.html URL]
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*Editors of Nature. 2004. Futures of Artificial Life. Nature. Vol. 431: 613. (Editorial that addresses ethical considerations), [http://www.bio.davidson.edu/courses/synthetic/papers/Synthetic_Editorial.pdf URL]
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===Research Papers in Synthetic Biology===
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*Timothy S. Gardner, Charles R. Cantor, and James J. Collins. 2000. Construction of a genetic toggle switch in Escherichia coli. Nature. Vol. 403. 339 - 342. (Bistable gene regulatory network, toggled by transient chemical or thermal induction, to serve as cellular memory)
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*Robert T. Batey, Sunny D. Gilbert, and Rebecca K. Montange. 2004. Structure of a Natural Guanine-responsive Riboswitch Complexed with a Metabolite Hypoxanthine. Nature. Vol. 432. 411 - 415. (Distinguishes Riboswitches from Aptamers and Antiswitches; also shows 3D structure of aptamer and ligand)
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*News Summary of Batey et al. 2004. (Batey et al., paper above)
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*Laising Yen et al. 2004. Exogenous Controlof Mammalian Gene Expression through Modulation of RNA Self-cleavage. Nature. Vol. 431: 471 - 476. (mRNA-mediated regulation of translation)
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*Yina Kuang, Israel Biran, and David R. Walt. 2004. Simultaneously Monitoring Gene Expression Kinetics and Genetic Noise in Single Cells by Optical Well Arrays. Analytical Chemistry. Vol. 76: 6282 - 6286. (Analysis of two promoters)
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*Thomas Bulter, Sun-Gu Lee, Wilson WaiChun Wong, Eileen Fung, Michael R. Conner, and James C. Liao. 2004. Design of artificial cell-cell communication using gene and metabolic networks. PNAS. 101(8): 2299-2304. (Quorum sensor using acetate signal)
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*Hideki Kobayashi, Mads Kaern, Michihiro Araki, Kristy Chung, Timothy S. Gardner, Charles R. Cantor, and James J. Collins. Programmable cells: Interfacing natural and engineered gene networks. PNAS. 101(22): 8414-8419. (Toggle switch interfaced with 1) SOS signaling pathway for DNA damage response and 2) quorum sensing signalling pathway)
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*Sara Hooshangi, Stephan Thiberge, and Ron Weiss. 2005. Ultrasensitivity and noise propagation in a synthetic transcriptional cascade. PNAS. 102(10): 3581–3586. (Basic Research Paper)
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*Bayer, Travis S. and Christina D. Smolke. 2005. Programable ligand-conrolled riboregulators of eukaryotic gene expression. Nature Biotechnology. 23 (3): 337 - 343. (Antiswithces that turn off or on mRNA translation, regulated by amptamer binding ligands)
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*Isaacs, Farren J. and James J. Collins. 2005. Plug-and-play with RNA. Nature Biotechnology. 23 (3): 306 -307. (Commentary on Bayer & Smolke, 2005.)
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* Subhayu Basu, Yoram Gerchman, Cynthia H. Collins, Frances H. Arnold and Ron Weiss. 2005. A synthetic multicellular system for programmed pattern formation. Nature. Vol. 434:1130-1134 (Cool patterns, seeded with senders, with receivers responding to chemical gradients)
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==Possible Fun Groups==
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#[[Awards Panel]]
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#[[Jamboree Planning]]
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#[[Editorial Board]]
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#[[Standards of Practice]]
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#[[iGEM 2006 Planning]]
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#[[Others (Publicity?)]]
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==Resources==
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#[[Blue Heron Point of Contact]]
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#[[Part Nicknames]]
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#[[Lab Protocols]]
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Please see [http://meta.wikipedia.org/wiki/MediaWiki_i18n documentation on customizing the interface]
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and the [http://meta.wikipedia.org/wiki/MediaWiki_User%27s_Guide User's Guide] for usage and configuration help.
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Revision as of 21:22, 26 May 2005

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