Buffer Bacteria
From 2006.igem.org
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=Intro= | =Intro= | ||
- | The idea is to use bacteria as a buffer for a specific substance. | + | The idea is to use bacteria as a buffer for a specific substance. |
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=Principle= | =Principle= | ||
When the concentration of the specific substance rises above a threshold, the bacteria generates something that neutralizes it. When it falls below a certain threshold, the bacteria somehow manages to replenish it. Could be pH, but could be something else, e.g. protein, metabolite, etc... | When the concentration of the specific substance rises above a threshold, the bacteria generates something that neutralizes it. When it falls below a certain threshold, the bacteria somehow manages to replenish it. Could be pH, but could be something else, e.g. protein, metabolite, etc... | ||
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=The Stock-based approach= | =The Stock-based approach= | ||
==Basic Idea== | ==Basic Idea== | ||
- | The higher the | + | The higher the concentration of substance A, the higher the rate of converting it so some other product B (stock). The lower the concentration of substance A, the higher the rate of converting stock B into A. |
This system could be tuned to hold the concentration of A at a specific level. | This system could be tuned to hold the concentration of A at a specific level. | ||
+ | |||
==Possible Extensions== | ==Possible Extensions== | ||
When there is a lack of A and stock B, then there could be active production A. | When there is a lack of A and stock B, then there could be active production A. |
Latest revision as of 11:39, 4 August 2005
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Contents |
Intro
The idea is to use bacteria as a buffer for a specific substance.
Principle
When the concentration of the specific substance rises above a threshold, the bacteria generates something that neutralizes it. When it falls below a certain threshold, the bacteria somehow manages to replenish it. Could be pH, but could be something else, e.g. protein, metabolite, etc... Ideally, this system would be general enough to work with different kinds of substances.
The Stock-based approach
Basic Idea
The higher the concentration of substance A, the higher the rate of converting it so some other product B (stock). The lower the concentration of substance A, the higher the rate of converting stock B into A. This system could be tuned to hold the concentration of A at a specific level.
Possible Extensions
When there is a lack of A and stock B, then there could be active production A.
Discussion
>> for comments, questions and temporary remarks go to the Talk:Buffer_Bacteria
Back to ETH Zurich main page.