Brown:March142006
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Present: John, Kara, Angela, Annie, Jessie, Peter, Brendan, Katherine, Victoria, Meghan | Present: John, Kara, Angela, Annie, Jessie, Peter, Brendan, Katherine, Victoria, Meghan | ||
| + | |||
| + | ===Journal Club Presentation=== | ||
| + | |||
| + | ====Construction of a Genetic Toggle Switch in E. Coli==== | ||
| + | |||
| + | by Victoria and Meghan | ||
| + | |||
| + | *purpose: to integrate theory and experiment by constructing and testing a synthetic, bistable gene circuit (Toggle switch) based on the predictions of a simple mathematical model | ||
| + | *integrate (mathetic) theory and (biology) experiment | ||
| + | *mathematical models supposed to predict how much transcribed, testing expected outcomes | ||
| + | *took a switch that self-regulates and has inducer (heat, chemical) that starts | ||
| + | *prediction was wrong due to gene variability | ||
| + | *simplest, as few reagents as possible better | ||
| + | *specialized promoters | ||
| + | *ribozyme binding sites, harnessed in plasmid; ensure that they are turned into proteins individually | ||
| + | *genetic engineering (memory device) insert into something that you would want to be turned on for a long time | ||
| + | *registry of biological parts at MIT; biological switch, wire linked together (electronic diagramà biological diagram | ||
==ACTIONS== | ==ACTIONS== | ||
Revision as of 00:32, 22 March 2006
Contents |
Meeting Minutes for March 14, 2006
Assignment of roles
Community Maker - Nick, Megan
Notetaker/Organizer (Secretary) - Angela
Journal Club Coordinator - Elena
Fundraising/PR
- Julie: Fundraising, Sheldon
- Brendan: PR
- Elaine: helping both
Faculty Liaison - Victoria
Wiki Development - Peter
Research - Annie, Sheldon
"Benevolent Dictator" =) - John
Commercialization Potential (patents, etc)
Industry Laison
We have lab space in JWW!!!
Meeting Minutes for March 21, 2006
Present: John, Kara, Angela, Annie, Jessie, Peter, Brendan, Katherine, Victoria, Meghan
Journal Club Presentation
Construction of a Genetic Toggle Switch in E. Coli
by Victoria and Meghan
- purpose: to integrate theory and experiment by constructing and testing a synthetic, bistable gene circuit (Toggle switch) based on the predictions of a simple mathematical model
- integrate (mathetic) theory and (biology) experiment
- mathematical models supposed to predict how much transcribed, testing expected outcomes
- took a switch that self-regulates and has inducer (heat, chemical) that starts
- prediction was wrong due to gene variability
- simplest, as few reagents as possible better
- specialized promoters
- ribozyme binding sites, harnessed in plasmid; ensure that they are turned into proteins individually
- genetic engineering (memory device) insert into something that you would want to be turned on for a long time
- registry of biological parts at MIT; biological switch, wire linked together (electronic diagramà biological diagram
ACTIONS
- Victoria will go to SAO to get info about table for ADOCH
- possibly also a web page/link to Brown iGEM
- have a site for prospective students to see who we are, as well as our contact info
- also, for everyone: think of ways to gain more attention
- Everyone: create a section on the wiki for the category you are overseeing
- Create a community portal:
- serve as a site that can be linked possibly from admissions page
- emphasizing that we are cross-disciplinary undergraduates performing research at Brown University, even several freshmen involved
- have our slightly more colorful biolographical infos attached
- Possible ideas for our project?
- Victoria/Megan doing the Journal Club presentation next week.
