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| - | '''<big>iGEM 2005</big> - The summer 2005 intercollegiate Genetically Engineered Machine competition.'''
| + | __NOTOC__ |
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| | | | |
| - | ==Participating Schools== | + | <font size=4>Note: The [http://igem.org iGEM 2008 Wiki] can be found here!</font> |
| | | | |
| - | {| width=400 align=center
| + | <font size=1>This wiki is archived and the contents frozen. Please update your links.</font> |
| - | |[[Berkeley]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Berkeley Parts]
| + | |
| - | |[[Caltech]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Caltech Parts] [http://www.cds.caltech.edu/~murray/synbio/wiki/index.php WIKI]
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| - | |[[Cambridge]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Cambridge Parts] [http://www.ccbi.cam.ac.uk/iGEM2005/index.php/Main_Page WIKI]
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| - | |[[Davidson]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Davidson Parts]
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| - | |-
| + | |
| - | |[[ETH Zurich]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_ETHZ Parts]
| + | |
| - | |[[Harvard]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Harvard Parts] [http://karma.med.harvard.edu/wiki/iGEM_2005 WIKI]
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| - | |-
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| - | |[http://model.mit.edu/igem/index.php?title=People MIT] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_MIT Parts] [http://model.mit.edu/igem WIKI]
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| - | |[[Oklahoma]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Oklamhoma Parts]
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| - | |[[Penn State]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Penn_State Parts]
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| - | |[[Princeton]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Princeton Parts] [http://ehukai.ee.princeton.edu/wi/index.php WIKI]
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| - | |-
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| - | |[[Toronto]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Toronto Parts]
| + | |
| - | |[[UCSF]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_UCSF Parts]
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| - | |-
| + | |
| - | |[[UT Austin]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_UTAustin Parts]
| + | |
| - | |[http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Registry Registry Parts]
| + | |
| - | |}
| + | |
| | | | |
| - | ==Events==
| |
| - | *[http://parts2.mit.edu/r/parts/htdocs/iGEM2005/ttt.cgi Teacher's Workshop] - May 15-15, 2005
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| - | **[[Parts, Devices, Systems & Engineering Theory]]
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| - | **[[Risks and Rewards]]
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| - | **[[Notes on Tom Knight's talk]]
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| - | **[http://web.mit.edu/endy/www/scraps/talks/iGEM/Silver.yeast.ppt Pam Silver's yeast powerpoint]
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| - | *Jamboree, November 5-6, 2005 (to change the name of the Jamboree, please send Drew Endy a check for $30,000,000)
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| | | | |
| - | ==Papers for Students to Read==
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| - | ===General Review Papers===
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| | | | |
| - | *A. Malcolm Campbell. 2005. Meeting Report: Synthetic Biology Jamboree for Undergraduates. Cell Biology Education. 4: 19 - 23. (Meeting Report for 2004 Jamboree) [http://www.cellbioed.org/pdf/04-11-0047.pdf URL]
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| - | *Dan Ferber. 2004. Microbes Made to Order. Science. Vol. 303: 158 - 161. (Good general overview), [http://www.sciencemag.org/cgi/content/full/303/5655/158 URL]
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| | | | |
| - | *Jeff Hasty, David McMillen, and J. J. Collins. 2002. Engineered Gene Circuits. Nature. Vol. 420: 224 - 230. (Scholarly Review Paper), [http://www.nature.com/nature/journal/v420/n6912/abs/nature01257_fs.html URL]
| + | <table width=100% height=5px><tr><td bgcolor="#2171B8" align="center"><font color=#ffffff size=1></font></td></tr></table> |
| | | | |
| - | *Philip Ball. 2004. Starting from Scratch. Nature. Vol. 431: 624 - 626. (OK general overview), [http://www.nature.com/news/2004/041004/pf/431624a_pf.html URL]
| + | <font size=4>'''iGEM 2006''' - The international Genetically Engineered Machine competition</font> |
| | + | <br> |
| | + | ''iGEM is an international arena where student teams compete to design and assemble engineered machines using advanced genetic components and technologies.'' |
| | + | <font size=1>[http://2006.igem.org/About_iGEM Learn more.]</font> |
| | + | <table width=100% height=5px><tr><td bgcolor="#2171B8" align="center"><font color=#ffffff size=1></font></td></tr></table> |
| | | | |
| - | *Editors of Nature. 2004. Futures of Artificial Life. Nature. Vol. 431: 613. (Editorial that addresses ethical considerations), [http://www.bio.davidson.edu/courses/synthetic/papers/Synthetic_Editorial.pdf URL]
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| | | | |
| - | ===Research Papers in Synthetic Biology=== | + | <div id="menu"> |
| | + | {|cellspacing="1" style="text-align:left" |
| | | | |
| - | *Timothy S. Gardner, Charles R. Cantor, and James J. Collins. 2000. Construction of a genetic toggle switch in Escherichia coli. Nature. Vol. 403. 339 - 342. (Bistable gene regulatory network, toggled by transient chemical or thermal induction, to serve as cellular memory)
| + | | {{Click || image=buttonschool.gif | link=Schools_Participating_in_iGEM_2006 | width=30px | height=30px }} |
| | + | |<font size="2" color="black">'''Meet the [[Schools_Participating_in_iGEM_2006|37 teams]] participating in 2006'''</font> |
| | + | |[[image:Verticalrule.png]] |
| | | | |
| - | *Robert T. Batey, Sunny D. Gilbert, and Rebecca K. Montange. 2004. Structure of a Natural Guanine-responsive Riboswitch Complexed with a Metabolite Hypoxanthine. Nature. Vol. 432. 411 - 415. (Distinguishes Riboswitches from Aptamers and Antiswitches; also shows 3D structure of aptamer and ligand)
| + | | {{Click || image=buttonprepare.gif | link=Resources | width=30px | height=30px }} |
| | + | |<font size="1" color="black">See [[Resources |teaching resources]] to learn about our unique methods</font> |
| | + | |[[image:Verticalrule.png]] |
| | | | |
| - | *News Summary of Batey et al. 2004. (Batey et al., paper above)
| + | | {{Click || image=registry.png | link=Main_Page | width=45px | height=45px }} |
| | + | |<font size="1" color="green">'''Ready to build?''' </font><font size="1" color="black">Go to the [http://partsregistry.org Registry] for BioBrick parts and tools</font> |
| | + | |[[image:Verticalrule.png]] |
| | | | |
| - | *Laising Yen et al. 2004. Exogenous Controlof Mammalian Gene Expression through Modulation of RNA Self-cleavage. Nature. Vol. 431: 471 - 476. (mRNA-mediated regulation of translation)
| + | | {{Click || image=buttonambassador.gif | link=IGEM_Ambassador_Program | width=40px | height=40px }} |
| | + | | <font size="1" color="black">The [[IGEM_Ambassador_Program|Ambassador Program]] helps teams around the globe succeed</font> |
| | + | |[[image:Verticalrule.png]] |
| | | | |
| - | *Yina Kuang, Israel Biran, and David R. Walt. 2004. Simultaneously Monitoring Gene Expression Kinetics and Genetic Noise in Single Cells by Optical Well Arrays. Analytical Chemistry. Vol. 76: 6282 - 6286. (Analysis of two promoters)
| + | | {{Click || image=dontpanic.jpg | link=help! | width=30px | height=30px }} |
| | + | |<font size="1" color="black">Give and get [[help!|help information and FAQs]] here.</font> |
| | | | |
| - | *Thomas Bulter, Sun-Gu Lee, Wilson WaiChun Wong, Eileen Fung, Michael R. Conner, and James C. Liao. 2004. Design of artificial cell-cell communication using gene and metabolic networks. PNAS. 101(8): 2299-2304. (Quorum sensor using acetate signal)
| + | |- |
| | + | |} |
| | + | </div> |
| | | | |
| - | *Hideki Kobayashi, Mads Kaern, Michihiro Araki, Kristy Chung, Timothy S. Gardner, Charles R. Cantor, and James J. Collins. Programmable cells: Interfacing natural and engineered gene networks. PNAS. 101(22): 8414-8419. (Toggle switch interfaced with 1) SOS signaling pathway for DNA damage response and 2) quorum sensing signalling pathway)
| + | {| border="0" cellpadding="0" cellspacing="0" width="460px"; border: 2px solid #2171B8;" |
| | + | | |
| | + | | valign="top" style="padding: 0px; border: 2px solid #2171B8;"| |
| | + | [http://2006.igem.org/wiki/index.php/Jamboree https://static.igem.org/mediawiki/2006/8/8f/JamboreeSmall.png] |
| | + | | valign="top" style="padding: 0px; border: 2px solid #2171B8;"| |
| | + | [http://igem2006.com https://static.igem.org/mediawiki/2006/f/f4/IGEMAboveCommunitysmall.png] |
| | + | |} |
| | | | |
| - | *Sara Hooshangi, Stephan Thiberge, and Ron Weiss. 2005. Ultrasensitivity and noise propagation in a synthetic transcriptional cascade. PNAS. 102(10): 3581–3586. (Basic Research Paper)
| + | {| border="0" cellpadding="0" cellspacing="0" width="480px"; background-color: #CCCCCC; border: 2px solid #2171B8;" |
| | + | |valign="top" style="padding:0px; border: 2px solid #2171B8;" width="470px"| |
| | + | [[image:Radio-iGEM-current-events.gif|Current Events]] |
| | | | |
| - | *Bayer, Travis S. and Christina D . Smolke. 2005. Programmable ligand-controlled riboregulators of eukaryotic gene expression. Nature Biotechnology. 23 (3): 337 - 343. (Antiswithces that turn off or on mRNA translation, regulated by amptamer binding ligands)
| + | <font size="1" color="red">>></font> Registration for iGEM 2007 is now open at [http://www.igem2007.com www.igem2007.com] |
| | + | *Visit the iGEM 2006 web site detailing results from the 2006 Jamboree and public relations information @ [http://www.igem2006.com www.igem2006.com]. |
| | + | *Don't forget to mark your Favorite Parts in the Registry. [http://partsregistry.org/Help:Favorite_Parts Here's how] |
| | + | *Check out the Jamboree 2006 [[Jamboree:Images|Image Gallery]] |
| | + | *See the latest Jamboree information [[Jamboree|here]]. |
| | | | |
| - | *Isaacs, Farren J. and James J. Collins. 2005. Plug-and-play with RNA. Nature Biotechnology. 23 (3): 306 -307. (Commentary on Bayer & Smolke, 2005.)
| |
| | | | |
| - | * Subhayu Basu, Yoram Gerchman, Cynthia H. Collins, Frances H. Arnold and Ron Weiss. 2005. A synthetic multicellular system for programmed pattern formation. Nature. Vol. 434:1130-1134 (Cool patterns, seeded with senders, with receivers responding to chemical gradients) [http://www.nature.com/nature/journal/v434/n7037/abs/nature03461.html URL]
| |
| | | | |
| - | ===Mathematical Modeling in Synthetic Biology===
| |
| - | * Hasty J, McMillen D, Isaacs F, Collins JJ. 2001. Computational studies of gene regulatory networks: in numero molecular biology. Nat Rev Genet. 2001 Apr;2(4):268-79.
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| - | * Guet, Călin C., Elowitz, Michael B., Hsing, Weihong, Leibler, Stanislas Combinatorial Synthesis of Genetic Networks Science 2002 296: 1466-1470
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| | | | |
| - | * McAdams HH, Arkin A. Simulation of prokaryotic genetic circuits. Annu Rev Biophys Biomol Struct. 1998; 27:199-224. [http://dx.doi.org/10.1146/annurev.biophys.27.1.199 Link]
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| | | | |
| - | ==Possible Fun Groups== | + | <font color=mediumblue>'''Check for [[Current Events|Past Events]]...''' |
| - | #[[Awards Panel]]
| + | |
| - | #[[Jamboree Planning]]
| + | |
| - | #[[Editorial Board]]
| + | |
| - | #[[Standards of Practice]]
| + | |
| - | #[[iGEM 2006 Planning]]
| + | |
| - | #[[Others (Publicity?)]]
| + | |
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| | | | |
| - | ==Resources== | + | | width="480px" valign="top" style="padding: 0px; border: 2px solid #2171B8;"| |
| - | #[[Blue Heron Point of Contact]] | + | [[image:Radio-iGEM-News.gif |iGEM News]] |
| - | #[[Part Nicknames]]
| + | |
| - | #[[Lab Protocols]]
| + | |
| | | | |
| - | Please see [http://meta.wikipedia.org/wiki/MediaWiki_i18n documentation on customizing the interface]
| + | <font size="1" color="red">>> </font> [http://www.discover.com/issues/dec-06/cover/ Jay Keasling - Scientist of the Year] <small>Discover Magazine</small> |
| - | and the [http://meta.wikipedia.org/wiki/MediaWiki_User%27s_Guide User's Guide] for usage and configuration help.
| + | *[http://www.sciencedaily.com/releases/2006/11/061114193826.htm Gene Machine: Cells Engineered To Prevent Sepsis Win Synthetic Biology Competition] <small>Science Daily</small> |
| - | [http://www.town-china.cn 中央吸尘][http://www.town-china.cn 新风系统] | + | *[http://science.slashdot.org/article.pl?sid=06/11/06/1913228&threshold=-1 Genetically Engineered Machines Competition] <small>Slashdot.org</small> |
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| + | *[http://www.technologyreview.com/read_article.aspx?id=17716&ch=biotech Bizarre bacterial creations] <small>Technology Review</small> |
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| + | <font color=mediumblue>'''add your own [[iGEM News|iGEM News]]...''' |
| | + | |} |
| | | | |
| - | ==Funding== | + | <font size=1>iGEM is an initiative of the MIT [http://icampus.mit.edu/ iCampus] program, which is funded by Microsoft Corp. iCampus sponsors faculty innovations in educational technology, helps incubate them through classroom use, and promotes their adoption, evaluation and continued evolution through worldwide multi-institutional cooperation.</font> |
| | | | |
| - | iGEM is an initiative of the MIT [http://icampus.mit.edu/ iCampus] program, which is funded by Microsoft Corp. iCampus sponsors faculty innovations in educational technology, helps incubate them through classroom use, and promotes their adoption, evaluation and continued evolution through worldwide multi-institutional cooperation. | + | <hr> |
| - | [http://www.town-china.cn 中央吸尘][http://www.town-china.cn 新风系统] | + | <font size=1; color="LightSlateGray">iGEM Competition c/o 32 Vassar Street, Room 314, Cambridge, MA 02139 (617) 258 5244 | [[join_igem|Join iGEM]] | Support iGEM </font> |
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