ETH 2006 Half adder
From 2006.igem.org
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''→ Illustration of the concepts: '' | ''→ Illustration of the concepts: '' | ||
| - | * [[media:Half-adder.pdf| | + | * [[media:Half-adder.pdf|slides]] (pdf, 352KB) |
* [[media:Half-adder-handout.pdf|handout]] (pdf, 268KB) | * [[media:Half-adder-handout.pdf|handout]] (pdf, 268KB) | ||
====Main Goal:==== | ====Main Goal:==== | ||
| - | + | # Write something with a chemical on a petri plate (like '''ETH''' for example) | |
| - | + | # Let Bacteria grow uniformly on the plate | |
| - | + | # Expose the plate to a picture (black and white) of the same pattern | |
| - | + | # Result: | |
| - | + | #*Bacteria gets green when pattern on the plate and picture match (light and chemical) | |
| - | + | #*Bacteria does not express fluorescent protein when pattern on the plate and picture match (no light and no chemical) | |
| - | + | #*Bacteria gets red when pattern on the plate and picture do not match | |
====Implementation from the ingenieur point of view==== | ====Implementation from the ingenieur point of view==== | ||
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*a chemical sensible promoter (chemical to be defined) | *a chemical sensible promoter (chemical to be defined) | ||
*we would need to give a kind of first signal to the system (to don't have light reactions before a certain moment, otherwise we have to work in a dark room...), an activation signal after the bacterias have grown on the plate | *we would need to give a kind of first signal to the system (to don't have light reactions before a certain moment, otherwise we have to work in a dark room...), an activation signal after the bacterias have grown on the plate | ||
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==== Pro's & Con's==== | ==== Pro's & Con's==== | ||
Latest revision as of 14:42, 26 October 2006
back to → ETH 2006 Main Page → Meat Monitor idea → other project ideas
Contents |
Half-adder or Full-adder
An implementation of a half-adder or full-adder: 1-bit adder with carry
- [http://en.wikipedia.org/wiki/Full_adder half/full adder in wikipedia]
Idea: Pattern recognition
→ Illustration of the concepts:
Main Goal:
- Write something with a chemical on a petri plate (like ETH for example)
- Let Bacteria grow uniformly on the plate
- Expose the plate to a picture (black and white) of the same pattern
- Result:
- Bacteria gets green when pattern on the plate and picture match (light and chemical)
- Bacteria does not express fluorescent protein when pattern on the plate and picture match (no light and no chemical)
- Bacteria gets red when pattern on the plate and picture do not match
Implementation from the ingenieur point of view
- Half Adder
- = opportunity to build an AND and an XOR Gate
Implementation from the biologist point of view
- AND Gate: presence of chemical induces the production of an inactive protein, which is activated by a second protein (produced when light is present): the first protein is then activating GFP production
- XOR Gate: I think Marko had a good idea about that (I didn't really got it)
- a light sensible promoter (there are some, see [http://partsregistry.org/Featured_Parts:Light_Sensor here])
- a chemical sensible promoter (chemical to be defined)
- we would need to give a kind of first signal to the system (to don't have light reactions before a certain moment, otherwise we have to work in a dark room...), an activation signal after the bacterias have grown on the plate
Pro's & Con's
Pro's:
- meaningful from engineering point
- valuable parts for synthetic biology
- stepwise proceeding applicable (→ intermediate and partial results!)
- experiments visually attractive
- probably simple enough
Con's:
- cheap copy of “bio-film” project ([http://partsregistry.org/cgi/htdocs/SBC04/index.cgi iGEM 2004])
- sensational experiments, have little in common with half adder
- maybe that a big vision is lacking
- general/practical benefit? (counter-argument: is this required?)
- too simple?
