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- | Program History temp page
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- | == Program History ==
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- | During MIT's [[Iap 2003|Independent Activity Periods (IAP) of January 2003]], student teams designed biological oscillators coupled to fluorescent reporters. These genetic blinkers were intended to improve on Elowitz's Repressilator. One team coupled two oscillators to even out the oscillations. Another used cell-cell signaling to coordinate the oscillators in a colony. During the January [[Iap 2004|2004 IAP]], teams designed genetic systems to create cellular patterns varying from bull’s-eyes to polka dots and even dynamic designs where cells swim together. From these designs, standard biological parts were designed and synthesized.
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- | Summer of [[Igem 2004|2004 brought the first Synthetic Biology Competition]]. Student teams from five schools (Princeton, MIT, Caltech, UT Austin, and Boston University) competed to build cellular state machines and counters. The teams came together for a jamboree in early November to compare their results. The most graphic project was "photographic biofilm" that could capture an image.
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- | In the [[Igem 2005|summer of 2005]], student teams from thirteen schools (Berkeley, Caltech, Cambridge UK, Davidson, ETH Zurich, Harvard, MIT, Oklahoma, Penn State, Princeton, Toronto, UCSF, and UT Austin) participated in the 2005 International Genetically Engineered Machine (iGEM) competition. Later, during the first weekend of November, over 150 of these students, instructors, and PIs came together for a jamboree to share and celebrate their work.
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- | The [[Igem 2005]] student projects displayed the designs of chemotaxis regulation systems, cell-cell genetic communications systems, cellular/biological wires, thermometers, biological sketch pads (drawing systems), cellular relay races, a digital counter, and many more.
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- | While at this early stage none of the projects were fully functional, many of the required subsystems demonstrated correct operation. Some of the student teams are continuing to work on their projects. One surprising result of [[Igem 2005]] is that several of the schools have begun to incorporate Synthetic Biology into their undergraduate curriculum based on work from the 2005 event. Schools are now working on their [[Schools Participating in iGEM 2006|iGEM summer 2006]].
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- | <hr>
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- | [http://partsregistry.org/Help:BioBrick_Assembly http://partsregistry.org/wiki/images/f/ff/Bricks.png]
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- | BioBricks have been designed to be assembled using normal cloning techniques. Find out more about the diffrent types of [[Help:BioBrick Assembly|Assembly]]:
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- | *[[Assembly:Standard assembly|Standard Assembly]]
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- | *[[Assembly:Rolling assembly |Parallel Assembly]]
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- | *[[Assembly:Robotic assembly|Automated Assembly]]
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- | *[[Assembly:RBS-CDS issues|RBS-CDS Issues]]
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- | [http://partsregistry.org/Help:BioBrick_Tools http://partsregistry.org/wiki/images/9/93/Toolman.png]
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- | An overview of the Registry's computational tools and how one may go about using them as they look to design and develop parts, device and systems.
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- | '''Quicklinks:'''
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- | *[[Help:Toolbox Overview | Toolbox Overview]]
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- | *[[Help:Sandbox Overview | Sandbox Overview]]
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- | *[[Tutorial:Adding a Basic Part|Tutorial: How to add a basic BioBrick]]
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- | *[[Help:Standardization|Making BioBrick DNA]]
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| [[Image:2003-iap.jpg|thumb|85px]] | | [[Image:2003-iap.jpg|thumb|85px]] |
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- | Overview & links on how to physically assembly BioBricks
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- | *[http://openwetware.org/wiki/BioBricks_construction_tutorial How to perform a construction] - <small>A tutorial drawing on different [http://openwetware.org OpenWetware] protocols on how to make assemblies using Biobricks</small> | + | |
- | *[http://openwetware.org/wiki/BE.109:Schedule Genetic engineering] - <small>Recommended especially for wet-lab beginners! Introduction to genetic engineering and cloning techniques.</small>
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- | *[[Help: How to make agar|Agar/color coding]]
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| |} | | |} |
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