From 2006.igem.org

Short Overview. The project of the ETH Zurich team consists of the design and implementation in vivo of a gene circuit that can count up to 4. In essence, the counter uses two toggle switches, each storing 1 bit, to keep track of the 4 states. The design of the counter is highly modular, with the hope that it can be included as a unit in larger circuits, and also combined with further counter instances to keep track of a much larger number of states, up to (2^(n+1)) with n units. To facilitate further developments and integration to other projects, the counter is available in form of BioBricks. Among many exciting applications, the availability of a counter enables the execution of sequential instructions, and paves the way for the execution of artifical programs inside living cells.

Contents 1 News 2 Organisation 2.1 People 2.1.1 Students 2.1.2 Supervisors 2.1.3 Advisors

News

• 2005.10.18 The parts for the actual INPUT-module are ready, thanks to the hard work of Giorgia, Hervé, and Martje (not all test/debbuging parts though)
• 2005.10.07 Message from Blue Heron: Sequences for NOR are synthesized and will be verified and assembled next week.
• 2005.09.23 Sequences for NOR module ordered from Blue Heron

Organisation

People

Students

Simon Barkow	Christophe Dessimoz	Zlatko Franjcic
Dominic Frutiger	Robin Künzler	Urs A. Müller
Jonas Nart	Kristian Nolde	Alexander Roth
Tamara Ulrich	Giorgia Valsesia	Herve Vanderschuren

Supervisors

Jörg Stelling

Sven Panke

Eckart Zitzler

Advisors

Uwe Sauer	Martin Fussenegger	Andreas Hierlemann
Kay-Uwe Kirstein	Ruedi Aebersold