Brown:Projects
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Magnetotactic Bacteria
Avadin-Biotin Complex
To create magnetosomes covered in Avadin. The basic idea is to create a fusion protein from MagA and Avadin, then isolate the magnetic particles, which will now be coated in avadin. Avadin forms one of the strongest bindings known with the molecule biotin.
Bayer, E. A. and Wilchek, M. (1978). The avidin-biotin complex as a tool in molecular biology. Trends Biochem. Sci. 3, N237-N239.
http://www.weizmann.ac.il/Biological_Chemistry/scientist/Bayer/BayerAvidin.html
http://www.avidity.com/apps.html current applications of tagging biotin