Event Processing Device

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(Possible Implementation)
(Two Regulators (a+r))
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=Possible Implementation=
=Possible Implementation=
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==Two Regulators (a+r)==
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==Two Regulators (a,r)==
In the strategies below, the input PoPS regulates two proteins, an activator and a repressor. That has the advantage of being very simple, but requires that both proteins have roughly similar production and degradation speed.
In the strategies below, the input PoPS regulates two proteins, an activator and a repressor. That has the advantage of being very simple, but requires that both proteins have roughly similar production and degradation speed.
==="Basic" (Giorgia)===
==="Basic" (Giorgia)===

Revision as of 07:47, 18 August 2005

Contents

Module Description

In a nutshell, this module has 2 system boundaries, both of which are characterized by PoPS. Its purpose is to take a single input PoPS and output 2 different PoPS. One of the outputs should be high and the other low when S is high and vice versa when S is low.

Group Members

  • Christophe, Dominic (coordinator), Giorgia, Herve, Kristian, Zlatko

Group Meeting History

log 2005-08-17: Wednesday, ~13:00 @ polyterasse: Discussion of module, next steps, task distrib.

Possible Implementation

Two Regulators (a,r)

In the strategies below, the input PoPS regulates two proteins, an activator and a repressor. That has the advantage of being very simple, but requires that both proteins have roughly similar production and degradation speed.

"Basic" (Giorgia)

Antisense (Giorgia)

One Regulators (ar)

In the implementations below, the input PoPs regulate the production of a sole protein that somehow acts as activator and repressor. With only one regulator, production and degradation are perfectly uniform, which is good, but in some cases, it might be harder to obtain a symmetrical activity, which is bad.

AraC (Giorgia)

"Lunatic Activator" (Christophe)

Zinc Finger YY1 (Hervé)

Secondary Metabolism (Christophe)

Fusion Protein (Hervé)

Bidirectional Promoter (Hervé)

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