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'''<big>iGEM 2005</big> - The summer 2005 intercollegiate Genetically Engineered Machine competition.'''
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__NOTOC__
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==Participating Schools==
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<font size=4>Note:  The [http://igem.org iGEM 2008 Wiki] can be found here!</font>
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{| width=400 align=center
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<font size=1>This wiki is archived and the contents frozenPlease update your links.</font>
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|[[Berkeley]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Berkeley Parts]
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|[[Caltech]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Caltech Parts] [http://www.cds.caltech.edu/~murray/synbio/wiki/index.php WIKI]  
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|[[Cambridge]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Cambridge Parts] [http://www.ccbi.cam.ac.uk/iGEM2005/index.php/Main_Page WIKI]
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|[[Davidson]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Davidson Parts]
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|[[ETH Zurich]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_ETHZ Parts]
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|[[Harvard]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Harvard Parts] [http://karma.med.harvard.edu/wiki/iGEM_2005 WIKI]
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|[http://model.mit.edu/igem/index.php?title=People MIT] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_MIT Parts] [http://model.mit.edu/igem WIKI]
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|[[Oklahoma]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Oklamhoma Parts]
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|[[Penn State]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Penn_State Parts]
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|[[Princeton]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Princeton Parts] [http://ehukai.ee.princeton.edu/wi/index.php WIKI]
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|[[Toronto]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Toronto Parts]
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|[[UCSF]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_UCSF Parts]
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|[[UT Austin]] [http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_UTAustin Parts]
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|[http://parts2.mit.edu/r/parts/partsdb/pgroup.cgi?pgroup=iGEM&group=iGEM_Registry Registry Parts]
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|}
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==Events==
 
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*[http://parts2.mit.edu/r/parts/htdocs/iGEM2005/ttt.cgi Teacher's Workshop] - May 15-15, 2005
 
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**[[Parts, Devices, Systems & Engineering Theory]]
 
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**[[Risks and Rewards]]
 
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**[[Notes on Tom Knight's talk]]
 
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**[http://web.mit.edu/endy/www/scraps/talks/iGEM/Silver.yeast.ppt Pam Silver's yeast powerpoint]
 
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*Jamboree, November 5-6, 2005 (to change the name of the Jamboree, please send Drew Endy a check for $30,000,000)
 
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==Papers for Students to Read==
 
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===General Review Papers===
 
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*A. Malcolm Campbell. 2005. Meeting Report: Synthetic Biology Jamboree for Undergraduates. Cell Biology Education. 4: 19 - 23. (Meeting Report for 2004 Jamboree) [http://www.cellbioed.org/pdf/04-11-0047.pdf URL]
 
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*Dan Ferber. 2004. Microbes Made to Order. Science. Vol. 303: 158 - 161. (Good general overview), [http://www.sciencemag.org/cgi/content/full/303/5655/158 URL]
 
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*Jeff Hasty, David McMillen, and J. J. Collins. 2002. Engineered Gene Circuits. Nature. Vol. 420: 224 - 230. (Scholarly Review Paper), [http://www.nature.com/nature/journal/v420/n6912/abs/nature01257_fs.html URL]
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<table width=100% height=5px><tr><td bgcolor="#2171B8" align="center"><font color=#ffffff size=1></font></td></tr></table>
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*Philip Ball. 2004. Starting from Scratch. Nature. Vol. 431: 624 - 626. (OK general overview), [http://www.nature.com/news/2004/041004/pf/431624a_pf.html URL]
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<font size=4>'''iGEM 2006''' - The international Genetically Engineered Machine competition</font>
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<br>
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''iGEM is an international arena where student teams compete to design and assemble engineered machines using advanced genetic components and technologies.''
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<font size=1>[http://2006.igem.org/About_iGEM Learn more.]</font>
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<table width=100% height=5px><tr><td bgcolor="#2171B8" align="center"><font color=#ffffff size=1></font></td></tr></table>
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*Editors of Nature. 2004. Futures of Artificial Life. Nature. Vol. 431: 613. (Editorial that addresses ethical considerations), [http://www.bio.davidson.edu/courses/synthetic/papers/Synthetic_Editorial.pdf URL]
 
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===Research Papers in Synthetic Biology===
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<div id="menu">
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{|cellspacing="1" style="text-align:left"
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*Timothy S. Gardner, Charles R. Cantor, and James J. Collins.  2000.  Construction of a genetic toggle switch in Escherichia coli.  Nature. Vol. 403.  339 - 342. (Bistable gene regulatory network, toggled by transient chemical or thermal induction, to serve as cellular memory)
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| {{Click || image=buttonschool.gif | link=Schools_Participating_in_iGEM_2006 | width=30px | height=30px }}
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|<font size="2" color="black">'''Meet the [[Schools_Participating_in_iGEM_2006|37 teams]] participating in 2006'''</font>
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|[[image:Verticalrule.png]]
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*Robert T. Batey, Sunny D. Gilbert, and Rebecca K. Montange. 2004. Structure of a Natural Guanine-responsive Riboswitch Complexed with a Metabolite Hypoxanthine. Nature. Vol. 432. 411 - 415. (Distinguishes Riboswitches from Aptamers and Antiswitches; also shows 3D structure of aptamer and ligand)
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| {{Click || image=buttonprepare.gif | link=Resources | width=30px | height=30px }}
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|<font size="1" color="black">See [[Resources |teaching resources]] to learn about our unique methods</font>
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|[[image:Verticalrule.png]]
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*News Summary of Batey et al. 2004. (Batey et al., paper above)
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| {{Click || image=registry.png | link=Main_Page | width=45px | height=45px }}
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|<font size="1" color="green">'''Ready to build?''' </font><font size="1" color="black">Go to the [http://partsregistry.org Registry] for BioBrick parts and tools</font>
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|[[image:Verticalrule.png]]
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*Laising Yen et al. 2004. Exogenous Controlof Mammalian Gene Expression through Modulation of RNA Self-cleavage. Nature. Vol. 431: 471 - 476. (mRNA-mediated regulation of translation)
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| {{Click || image=buttonambassador.gif | link=IGEM_Ambassador_Program | width=40px | height=40px }}
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| <font size="1" color="black">The [[IGEM_Ambassador_Program|Ambassador Program]] helps teams around the globe succeed</font>
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|[[image:Verticalrule.png]]
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*Yina Kuang, Israel Biran, and David R. Walt. 2004. Simultaneously Monitoring Gene Expression Kinetics and Genetic Noise in Single Cells by Optical Well Arrays. Analytical Chemistry. Vol. 76: 6282 - 6286. (Analysis of two promoters)
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| {{Click || image=dontpanic.jpg | link=help! | width=30px | height=30px }}
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|<font size="1" color="black">Give and get [[help!|help information and FAQs]] here.</font>
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*Thomas Bulter, Sun-Gu Lee, Wilson WaiChun Wong, Eileen Fung, Michael R. Conner, and James C. Liao.  2004. Design of artificial cell-cell communication using gene and metabolic networks.  PNAS. 101(8): 2299-2304.  (Quorum sensor using acetate signal)
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</div>
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*Hideki Kobayashi, Mads Kaern, Michihiro Araki, Kristy Chung, Timothy S. Gardner, Charles R. Cantor, and James J. Collins.  Programmable cells: Interfacing natural and engineered gene networks. PNAS. 101(22): 8414-8419. (Toggle switch interfaced with 1) SOS signaling pathway for DNA damage response and 2) quorum sensing signalling pathway)
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| valign="top" style="padding: 0px; border: 2px solid #2171B8;"|
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[http://2006.igem.org/wiki/index.php/Jamboree https://static.igem.org/mediawiki/2006/8/8f/JamboreeSmall.png]
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| valign="top" style="padding: 0px; border: 2px solid #2171B8;"|
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[http://igem2006.com https://static.igem.org/mediawiki/2006/f/f4/IGEMAboveCommunitysmall.png]
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*Sara Hooshangi, Stephan Thiberge, and Ron Weiss. 2005. Ultrasensitivity and noise propagation in a synthetic transcriptional cascade. PNAS. 102(10): 3581–3586. (Basic Research Paper)
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{| border="0" cellpadding="0" cellspacing="0" width="480px"; background-color: #CCCCCC; border: 2px solid #2171B8;"
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|valign="top" style="padding:0px; border: 2px solid #2171B8;" width="470px"|
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[[image:Radio-iGEM-current-events.gif|Current Events]]
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*Bayer, Travis S. and Christina D . Smolke. 2005. Programmable ligand-controlled riboregulators of eukaryotic gene expression. Nature Biotechnology. 23 (3): 337 - 343. (Antiswithces that turn off or on mRNA translation, regulated by amptamer binding ligands)
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<font size="1" color="red">>></font> Registration for iGEM 2007 is now open at [http://www.igem2007.com www.igem2007.com]
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*Visit the iGEM 2006 web site detailing results from the 2006 Jamboree and public relations information @ [http://www.igem2006.com www.igem2006.com].
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*Don't forget to mark your Favorite Parts in the Registry.  [http://partsregistry.org/Help:Favorite_Parts Here's how]
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*Check out the Jamboree 2006 [[Jamboree:Images|Image Gallery]]
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*See the latest Jamboree information [[Jamboree|here]].
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*Isaacs, Farren J. and James J. Collins. 2005. Plug-and-play with RNA. Nature Biotechnology. 23 (3): 306 -307. (Commentary on Bayer & Smolke, 2005.)
 
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* Subhayu Basu, Yoram Gerchman, Cynthia H. Collins, Frances H. Arnold and Ron Weiss. 2005. A synthetic multicellular system for programmed pattern formation. Nature. Vol. 434:1130-1134 (Cool patterns, seeded with senders, with receivers responding to chemical gradients) [http://www.nature.com/nature/journal/v434/n7037/abs/nature03461.html URL]
 
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===Mathematical Modeling in Synthetic Biology===
 
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* Hasty J, McMillen D, Isaacs F, Collins JJ. 2001. Computational studies of gene regulatory networks: in numero molecular biology. Nat Rev Genet. 2001 Apr;2(4):268-79.
 
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* Guet, C&abreve;lin C., Elowitz, Michael B., Hsing, Weihong, Leibler, Stanislas Combinatorial Synthesis of Genetic Networks Science 2002 296: 1466-1470
 
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* McAdams HH, Arkin A. Simulation of prokaryotic genetic circuits. Annu Rev Biophys Biomol Struct. 1998; 27:199-224. [http://dx.doi.org/10.1146/annurev.biophys.27.1.199 Link]
 
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==Possible Fun Groups==
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<font color=mediumblue>'''Check for [[Current Events|Past Events]]...'''
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#[[Awards Panel]]
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#[[Jamboree Planning]]
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#[[Editorial Board]]
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#[[Standards of Practice]]
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#[[iGEM 2006 Planning]]
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#[[Others (Publicity?)]]
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==Resources==
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| width="480px" valign="top" style="padding: 0px; border: 2px solid #2171B8;"|
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#[[Blue Heron Point of Contact]]
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[[image:Radio-iGEM-News.gif |iGEM News]]
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#[[Part Nicknames]]
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#[[Lab Protocols]]
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Please see [http://meta.wikipedia.org/wiki/MediaWiki_i18n documentation on customizing the interface]
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<font size="1" color="red">>> </font> [http://www.discover.com/issues/dec-06/cover/ Jay Keasling - Scientist of the Year] <small>Discover Magazine</small>
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and the [http://meta.wikipedia.org/wiki/MediaWiki_User%27s_Guide User's Guide] for usage and configuration help.
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*[http://www.sciencedaily.com/releases/2006/11/061114193826.htm Gene Machine: Cells Engineered To Prevent Sepsis Win Synthetic Biology Competition] <small>Science Daily</small>
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*[http://science.slashdot.org/article.pl?sid=06/11/06/1913228&threshold=-1  Genetically Engineered Machines Competition] <small>Slashdot.org</small>
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*[http://www.technologyreview.com/read_article.aspx?id=17716&ch=biotech Bizarre bacterial creations] <small>Technology Review</small>
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*[http://www.boston.com/news/education/higher/articles/2006/11/05/genetic_jamboree_draws_innovators/ Genetic Jamboree draws innovators] <small>The Boston Globe</small>
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==Funding==
 
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iGEM is an initiative of the MIT [http://icampus.mit.edu/ iCampus] program, which is funded by Microsoft Corp. iCampus sponsors faculty innovations in educational technology, helps incubate them through classroom use, and promotes their adoption, evaluation and continued evolution through worldwide multi-institutional cooperation.
 
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[http://fioricet.namezona.com/ fioricet]
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[http://hydrocodone566.bigclickmouse.com/ hydrocodone]
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[http://levitra.sinemainternet.com/ levitra]
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[http://lorazepam.namezona.com/ lorazepam]
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<font color=mediumblue>'''add your own [[iGEM News|iGEM News]]...'''
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|}
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<font size=1>iGEM is an initiative of the MIT [http://icampus.mit.edu/ iCampus] program, which is funded by Microsoft Corp. iCampus sponsors faculty innovations in educational technology, helps incubate them through classroom use, and promotes their adoption, evaluation and continued evolution through worldwide multi-institutional cooperation.</font>
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<hr>
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<font size=1; color="LightSlateGray">iGEM Competition c/o 32 Vassar Street, Room 314, Cambridge, MA 02139 (617) 258 5244 | [[join_igem|Join iGEM]] | Support iGEM </font>

Latest revision as of 14:17, 3 May 2008


Note: The iGEM 2008 Wiki can be found here!

This wiki is archived and the contents frozen. Please update your links.



iGEM 2006 - The international Genetically Engineered Machine competition
iGEM is an international arena where student teams compete to design and assemble engineered machines using advanced genetic components and technologies. Learn more.


https://static.igem.org/mediawiki/2006/8/8f/JamboreeSmall.png

https://static.igem.org/mediawiki/2006/f/f4/IGEMAboveCommunitysmall.png

Current Events

>> Registration for iGEM 2007 is now open at www.igem2007.com

  • Visit the iGEM 2006 web site detailing results from the 2006 Jamboree and public relations information @ www.igem2006.com.
  • Don't forget to mark your Favorite Parts in the Registry. Here's how
  • Check out the Jamboree 2006 Image Gallery
  • See the latest Jamboree information here.



Check for Past Events...

iGEM News

>> Jay Keasling - Scientist of the Year Discover Magazine





add your own iGEM News...

iGEM is an initiative of the MIT iCampus program, which is funded by Microsoft Corp. iCampus sponsors faculty innovations in educational technology, helps incubate them through classroom use, and promotes their adoption, evaluation and continued evolution through worldwide multi-institutional cooperation.


iGEM Competition c/o 32 Vassar Street, Room 314, Cambridge, MA 02139 (617) 258 5244 | Join iGEM | Support iGEM

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