Synthetic Counter (iGem2005 ETH Zurich)

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=Introduction=
=Introduction=
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=Counter Design=
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The past few years have seen the emergence of the field of synthetic biology, in which functional units are designed and built into cells for a particular purpose, and ultimately to improve our understanding of life. Previous work include
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=Design of the Counter=
=Methods=
=Methods=
=Results and Discussion=
=Results and Discussion=

Revision as of 13:10, 14 October 2005

Abstract. We report here the design and implementation in vivo of a gene circuit that can count up to 4. In essence, it uses two toggle switches, each storing 1 bit, to keep track of the 4 states. The design of the counter is highly modular, in the hope that it can be included as a unit in larger circuits, but also combined with similar units to keep track of a much larger number of states, up to (2^(n+1)) with n units. To facilitate further development and integration to other projects, the counter is available in form of BioBricks.


Contents

Introduction

The past few years have seen the emergence of the field of synthetic biology, in which functional units are designed and built into cells for a particular purpose, and ultimately to improve our understanding of life. Previous work include

Design of the Counter

Methods

Results and Discussion

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