Pulser

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Back to [[Quorum_Sensing_based| Development Group]].
=Intro & principle=
=Intro & principle=
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An oscillating clustering-despersing behavior.
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=The "Repellent" Approach=
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==Basic Idea==
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The idea would be to use an oscillatory network which in the high phase would trigger transcription of an aggregation factor and in low expression phase would trigger expression of a repellent.
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=Approach=
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Using this system with an appropriate oscillation period, we should be able to see a pulser on the plate. In the high expression phase, bacteria would aggregate and in the low phase they would separate and so on.
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The idea would be to use an oscillatory network which in the high  phase would
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==Challenges==
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* To realize this pulser, we need to look for a good repellent factor candidate.
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* An oscillator is needed.
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trigger transcription of an aggregation factor and in low expression phase would trigger
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==Implementation Strategies==
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* The possible aggregation factors are Antigen 43 or type 1 Fimbriae.  
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expression of a repellent.
+
-
 
+
-
 
+
-
Using this system with an appropriate oscillation period, we should be able to see
+
-
 
+
-
a pulser on the plate. In the high expression phase, bacteria would aggregate and in the
+
-
 
+
-
low phase they would separate and so on.
+
-
 
+
-
 
+
-
The possible aggregation factors are Antigen 43 or type 1 Fimbriae.
+
-
 
+
-
To realize this pulser, we need to look for a good repellent factor candidate.
+
=Discussion=
=Discussion=
>> for comments, questions and temporary remarks go to the [[Talk:Pulser]]
>> for comments, questions and temporary remarks go to the [[Talk:Pulser]]
 +
 +
Back to [[Quorum_Sensing_based| Development Group]].
Back to [[ETH Zurich]] main page.
Back to [[ETH Zurich]] main page.

Latest revision as of 10:49, 7 August 2005

Back to ETH Zurich main page.

Back to Development Group.

Contents

Intro & principle

An oscillating clustering-despersing behavior.

The "Repellent" Approach

Basic Idea

The idea would be to use an oscillatory network which in the high phase would trigger transcription of an aggregation factor and in low expression phase would trigger expression of a repellent.

Using this system with an appropriate oscillation period, we should be able to see a pulser on the plate. In the high expression phase, bacteria would aggregate and in the low phase they would separate and so on.

Challenges

  • To realize this pulser, we need to look for a good repellent factor candidate.
  • An oscillator is needed.

Implementation Strategies

  • The possible aggregation factors are Antigen 43 or type 1 Fimbriae.

Discussion

>> for comments, questions and temporary remarks go to the Talk:Pulser

Back to Development Group.

Back to ETH Zurich main page.

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