Template:ETH Sim Input Rate

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The input rates (PoPS) have been chosen in the range of mRNA transcription rate, which was estimated according to the following assumptions:

  • E.coli cytoplasm volume is approximately 6.7*10-16 l
  • average number of mRNA molecules: 10
  • → concentrationmRNA = 10/(6.7*10-16 * 6.022*1023) M = 0.0248 μM
  • at equilibrum, mRNA rate and degredation balance each other. Assuming half life period of 30min for mRNA, the result is
    →ratemRNA = concentrationmRNA * log(2)/30 μM/min = 5.7265e-04 μM/min
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