ETH Sim Mod AND tRNA

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help constants

constants legend

constant set: '2h prot. half life'

ETH Sim Mod AND tRNA 2h.jpg

simulated with these constants (constants legend)

        case '2h prot. half life'
            % approximate (median) concentration of I1/I2/I1p/I2p
            % used for k/K constants depending on this concentration
            stateT7R    = 250;
            
            k.T7R       = .1;               % []
            k.tRNA      = .1;               % []
            l.T7R       = 1/stateT7R;       % [1/(muM*min)]  depending on T7R
            l.T7Rd      = .1;               % [1/min]
            l.tRNA      = .1;               % [1/min]
            d.T7R       = log(2)/120;       % [1/min]
            d.T7Rd      = log(2)/120;       
            d.tRNA      = log(2)/(60*24*2);
            d.mT7R      = log(2)/30;
            d.mtRNA     = log(2)/30;
            d.mOut      = log(2)/30;
            d.Out       = log(2)/120;
            
            r.Out       = 0.1;              % []
            p.Out       = 0.1 * r.Out; % a*r  []
            l.Out       = 1;                % [1/min]
            K.Out       = stateT7R;         % muM--> depending on T7R
            n.Out       = 1;                % []

constant set: '5h prot. half life'

ETH Sim Mod AND tRNA 5h.jpg

simulated with these constants (constants legend)

        otherwise   %case '5h prot. half life'
            % approximate (median) concentration of I1/I2/I1p/I2p
            % used for k/K constants depending on this concentration
            stateT7R    = 400;
            
            k.T7R       = .1;               % []
            k.tRNA      = .1;               % []
            l.T7R       = 1/stateT7R;       % [1/(muM*min)]  depending on T7R
            l.T7Rd      = .1;               % [1/min]
            l.tRNA      = .1;               % [1/min]
            d.T7R       = log(2)/300;       % [1/min]
            d.T7Rd      = log(2)/300;       
            d.tRNA      = log(2)/(60*24*2);
            d.mT7R      = log(2)/30;
            d.mtRNA     = log(2)/30;
            d.mOut      = log(2)/30;
            d.Out       = log(2)/300;
            
            r.Out       = 0.1;              % []
            p.Out       = 0.1 * r.Out; % a*r  []
            l.Out       = 1;                % [1/min]
            K.Out       = stateT7R;         % muM--> depending on T7R
            n.Out       = 1;                % []
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