Brown:Projects

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[[Brown:iGEM portal 2006 |Home]]
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{{Brown navigation bar}}
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== Magnetotactic Bacteria ==
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==Avadin-Biotin Complex==
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<h3>Brown 2006 iGEM entry </h3>
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To create magnetosomes covered in AvadinThe basic idea is to create a fusion protein from MagA and Avadin, then isolate the magnetic particles, which will now be coated in avadinAvadin forms one of the strongest bindings known with the molecule biotin.
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As the race to the finish draws near for iGEM 2006, our team has compiled a detailed summary of our summers workThis includes our initial ideas, designs, models and the parts that we have added to the registry.  We began the summer with grand plans to design a game of bacterial freeze tag, modeled after the popular children's game where one player tries to catch the otherOur efforts were then switched to the extension of the bi-stable toggle switch and the design of a tri-stable toggle switch.  Our projects highlight the team's creative and innovative approaches to designing and engineering working biological systems.
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Bayer, E. A. and Wilchek, M. (1978). The avidin-biotin complex as a tool in molecular biology. Trends Biochem. Sci. 3, N237-N239.
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Click here to see our BioBricks! [http://partsregistry.org/cgi/partsdb/pgroup.cgi?pgroup=iGEM2006partsregistry.org/cgi/partsdb/pgroup.cgi?pgroup=iGEM2006&group=Brown Brown iGEM 2006 Parts]
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http://www.weizmann.ac.il/Biological_Chemistry/scientist/Bayer/BayerAvidin.html  great review
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<h3>[[Brown:Bacterial Freeze Tag | Bacterial Freeze Tag]] </h3>
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http://www.avidity.com/apps.html  current applications of tagging biotin
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*[[Brown:Bacterial_Freeze_Tag#Overview |Overview]]
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*[[Brown:Bacterial_Freeze_Tag#Sender cell | Sender cell ]]
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*[[Brown:Bacterial_Freeze_Tag#Receiver cell | Receiver cell ]]
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*[[Brown:Bacterial_Freeze_Tag#Challenges| Challenges ]]
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<h3>[[Brown:Tri-Stable toggle switch|Tri-Stable toggle switch]]</h3>
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*[[Brown:Tri-Stable_toggle_switch|Introduction to the project]]
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*[[Brown:Tri-Stable toggle switch#Modeling the tri-stable toggle switch | Modeling the tri-stable switch]]
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*[[Brown:Tri-Stable toggle switch#What we achieved| What we achieved]]
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*[[Brown:Tri-Stable toggle switch#Challenges | Challenges ]]
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*[[Brown:Tri-Stable toggle switch#Challenges | Future work ]]
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<h3>[[Brown:Team logistics | Team Logistics ]] </h3>
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*[[Brown:Team logistics|How we got here]]
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*[[Brown:Team_logistics|Challenges]]
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*[[Brown:Team_logistics|Future work]]
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__NOTOC__

Latest revision as of 03:04, 2 November 2006

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Brown 2006 iGEM entry

As the race to the finish draws near for iGEM 2006, our team has compiled a detailed summary of our summers work. This includes our initial ideas, designs, models and the parts that we have added to the registry. We began the summer with grand plans to design a game of bacterial freeze tag, modeled after the popular children's game where one player tries to catch the other. Our efforts were then switched to the extension of the bi-stable toggle switch and the design of a tri-stable toggle switch. Our projects highlight the team's creative and innovative approaches to designing and engineering working biological systems.

Click here to see our BioBricks! Brown iGEM 2006 Parts

Bacterial Freeze Tag

Tri-Stable toggle switch

Team Logistics



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Past/present/future years